RU486 is a well-renowned way of medical abortion indicated to terminate the pregnancy in the early stages (less than 9 weeks). It contains Generic Mifepristone, an effective anti-progesterone and anti-glucocorticoid. RU486 pill is FDA approved to conclude a pregnancy. When used in combination with Misoprostol, it can cause pregnancy termination securely, if used within 9 weeks of gestation period.

The process of abortion has been frequently seen in our society.  A female may carry out abortion owing to a number of grounds, for instance it might be a financial reason, birth flaws or some undesired occurrences like rape, in which she could have been facing disgraceful and repulsive situation, when she gives, birth to a baby. Abortion is identified to be a defensive option to protect and maintain the emotional health of a woman by execution of pregnancy at premature stage. Not a logical answer, replied by a female when someone asks her, about the primary reason behind her unplanned abortion and on the other hand if she progress to decide surgical abortion, she might face disgraceful and other communal obligations. Now and then the phobic condition rises at the level, where she is left with no other option except only to commit suicide.

How RU486 works?

The hormone progesterone is blocked by RU486. First, Mifepristone acts by preventing the action of progesterone, natural female hormone required to maintain pregnancy. After that, Misoprostol works by emptying the mother's womb. Thus, pregnancy fragments do not develop ahead, and the lining of uterus is made soft. The uterine lining changes to push out pregnancy fragments from support of oxygen and nutrition. The embryo stops to exist, while cervix dilates. RU486 pill has other medical uses apart from abortion; it can be used for cure of Cushing syndrome and controlling high blood sugar level. Though, for terminating pregnancy, the medication is accountable for only disintegrating pregnancy fragments and putting fetus away from life support.

Dosage Indications of RU486 Pill:

You must take 3 tablets of RU486 (200mg each) orally with full glass of water. If abortion has not taken place, after 2 days, the user should take 2 tablets of Misoprostol (400mcg total).



If a dose of RU486 is missed, the chance of pregnancy execution may decline. Therefore, don't miss the dose of RU486; take the 3 tablets at the same time. Also exceeding the dose beyond the normal dose can amplify side effects and cause bleeding that is uncontrollable. In some cases of overdose, the female has to opt for surgical abortion because of complications.

Some of the side effects of RU486 abortion pill may include stomach cramps, light-headedness, vaginal bleeding, nausea, headache, diarrhea, vomiting, urinary tract irritation, tiredness.

Precautionary measures while taking RU486 Pill:

  • Avoid the use of this abortion pill with alcohol or nicotine.
  • Don't RU486 with Prednisone, Itraconazole and Ketoconazole.
  • RU486 is not advisable for ingestion during ectopic pregnancy or may bring about fallopian tube rupture and serious bleeding.
  • Avoid Generic Mifepristone if you are hypersensitive to it or have health complications related to heart, kidney, immune system, liver, blood, cancer, renal failure, and uterus.
  • Breastfeeding mother should stay away from this medication, as RU486 can result in damage to newborn’s health. In the same way, females consuming hormonal drugs or anti-progesterone medicines already should not use this pill, until a positive signal from physician.
  • Drowsiness is one of the side effects that come with the use of this pill. Therefore, the female is suggested to take sufficient rest and not be a part of any heavy physically straining activity until recovery.

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